GeneSight® Testing: Take Guesswork Out of Mental Health Meds

Trying mental health medications only to face side effects or no improvement wears you down fast. But, it doesn’t have to be a guessing game!

GeneSight® testing uses your unique DNA to pinpoint which psychiatric medications are most likely to be effective for you — that means fewer side effects, quicker relief, and a treatment plan you actually feel good about.

What Is GeneSight Testing?

GeneSight is a painless cheek swab. The DNA is tested at the lab for how your body processes and responds to more than 50 mental health medications.

Your psychiatrist receives a detailed report showing:

Which medications are likely to be effective

Which may cause side effects or be less effective for you

Guidance on optimal medication choices, dosages, and combinations

What to Expect from a GeneSight Test

The process is straightforward and the end result is clarity and confidence with medications that can help.

1 Quick, Painless Swab – A nurse collects a DNA sample using a cotton cheek swab (takes less than a minute).

2 Lab Analysis – The sample is sent to the lab and tested for how your genes interact the different medications.

3 Personalized Report – Within a day or so, your care team receives your report and reviews the best next steps for any medications.

Types of Medications Tested

Antidepressants: such as SSRIs (e.g. sertraline, fluoxetine), SNRIs (e.g. venlafaxine, duloxetine), and atypicals (e.g. bupropion, mirtazapine)
Anti-anxieties: such as SSRIs/SNRIs with anxiety indications (e.g. paroxetine, escitalopram)
Mood stabilizers: such as lamotrigine, valproate, and carbamazepine
Antipsychotics: such as aripiprazole, risperidone, olanzapine (used for bipolar, schizophrenia, and sometimes depression)
ADHD treatments: including stimulants (e.g. methylphenidate) and non-stimulants (e.g. atomoxetine)

Is GeneSight Right for You?

You don’t need to be on medication to benefit from GeneSight. It’s often used at the beginning of treatment to guide an initial prescription.

If you’re already taking medication, testing can confirm whether it’s the right fit, suggest better options, lower the risk of side effects, and guide care for co-occurring conditions.

GeneSight can be especially helpful if:

You’ve tried two or more medications without feeling better
You’ve stopped treatment because of side effects
You’re anxious about starting a new psychiatric medication
You want a more personalized, data-backed way to choose medications
You’re currently in treatment for depression, anxiety, ADHD, PTSD, substance use, or bipolar disorder

Key Benefits

GeneSight is supported by extensive research, including multiple peer-reviewed studies. Compared to treatment using traditional prescribing, patients using GeneSight experience:

50% greater improvement in symptoms ⓘ

40% drop in medication switching ⓘ

Other benefits of GeneSight testing include:

Reduces Trial-and-Error Prescribing
Improves Medication Outcomes
Leads to Faster Relief
Supports Medication Adherence
Guides Safer, Smarter Dosing
Helps Avoid Side Effects
Covered by Most Insurance Plans

Who GeneSigtht Is NOT For

Medications aren’t needed for every mental health issue.

Here at Indiana Center for Recovery you have access to cutting-edge non-medication treatment options too. Options like TMS, Biofeedback, and EMDR, as well as NAD+ IV Therapy and Spravato Ketamine Therapy.

Even if medications aren’t for you, you can find a treatment option here that is!

Yes, Treatment Is Covered By Insurance

Treatment here is usually in-network, so any cost to you is as low as possible — sometimes even zero. No one will be notified if you reach out. And, there’s no commitment to get answers.

Verify Your Insurance

Deeply Experienced, Nationally-Recognized Mental Health Experts

Dr. Michael Kane MD

Chief Medical Director (Psychiatrist)

Double board-certified in Psychiatry and Family Medicine, Dr. Kane has spent over a decade helping people navigate complex mental health challenges. His work is featured in publications like Newsweek and PsychCentral — known for combining cutting-edge science with deep empathy. He stays at the forefront of emerging research, ensuring patients have access to the most effective, up-to-date care.

Jackie Daniels LCSW

Director of Clinical Development (Therapist)

Jackie is a licensed therapist, national speaker, and in long-term recovery herself. With 20+ years of clinical experience, she’s led major statewide efforts—like expanding Naloxone access and launching Indiana University’s first Collegiate Recovery Program. She’s known treatment models that is not only evidence-based but deeply rooted in lived experience.

It Starts With a Simple Swab

If medications haven’t worked — or you want to feel better without the guesswork — GeneSight can help.

100% Confidential

No judgment

Covered by Most Insurance

(844) 650-0064

Verify Your Insurance

Thousands of Patients Benefited

I took did GeneSight testing, and am on the number one medication for me for depression, bipolar, PTSD, anxiety, and ADHD. It works for me.

Mango222

I found it really helpful!! I was on Prozac and Strattera. Turns out, Prozac majorly inhibits the effectiveness of a lot of medications such as other antidepressants and many ADHD meds. I just started Wellbutrin instead. It’s working a whole lot better!

Blackwell

My daughter had Genesight after she tried 3 different meds for combo ADHD and anxiety. It was spot on with the meds she had reactions to and gave us better options. I can't stress enough how good it is to know which anxiety meds to avoid.

Galamoon