What Is TMS Therapy?
Transcranial Magnetic Stimulation (TMS) is a safe, FDA-approved treatment for people struggling with mental health issues — especially when traditional medications haven’t worked.
It’s a non-invasive, drug-free option that uses gentle magnetic pulses to help reset brain activity, often improving symptoms in just a few weeks.
FDA-Approved Supported TMS Use
- Major Depressive Disorder (MDD) – Especially treatment-resistant depression
- Obsessive-Compulsive Disorder (OCD)
- Smoking Cessation
- Migraine (with Aura)

Research & Clinical Practice Supported TMS Use
- Generalized Anxiety Disorder (GAD)
- Post-Traumatic Stress Disorder (PTSD)
- Bipolar Depression – depressive phase only
- Schizophrenia – especially for auditory hallucinations
- Borderline Personality Disorder (BPD)
- Dysthymia – Persistent Depressive Disorder
- Panic Disorder
- Chronic Pain
- Attention-Deficit/Hyperactivity Disorder (ADHD) – exploratory use, mostly in adults
Substance Use Disorders
- Alcohol Use Disorder
- Cocaine Use Disorder
- Opioid Use Disorder – emerging research
Key Benefits of TMS
Research on the success of TMS therapy on treating specific disorders is growing every day, including:
- A 40–50% reduction in anxiety scores ⓘ
- 30-40% of patients with full remission of depression symptoms ⓘ
- A 38% improvement in symptom severity for OCD ⓘ
- 66% of patients with PTSD experience significant symptom reduction ⓘ
Beyond treatment of the specific condition, many patients report improved mood and a renewed sense of balance in their day-to-day life. They begin to feel more emotionally stable and connected, often for the first time in years.
There’s a noticeable return of motivation too — a desire to re-engage with life. Patients often rediscover an interest in activities they had lost, and feel less sadness or emotional emptiness. These shifts change how people are able to show up in relationships, work, and daily routines.
Physically, many experience better sleep, increased energy, and an overall sense of calm. With that stability comes a decrease in emotional outbursts, allowing them to respond to life’s challenges with greater patience and clarity.
Patients like most that TMS:
- Is FDA-approved, non-invasive treatment
- Requires no daily medication
- Has few to no side effects
- Is safe to use alongside most medications
- Can improve mood, focus, and motivation
- Has no recovery time — return to normal activities after
- Gives long-lasting symptom relief
- Is covered by most insurance plans
What to Expect During TMS Therapy
TMS sessions are calm and quick. Patients typically receive treatment multiple times per week for a month, though each session lasts less than a half hour. Patients may notice small shifts after just a few sessions and more meaningful changes by week 2 or 3.
Your care team will recommend the best type, duration, and frequency of TMS based on your symptoms, medical history, and treatment progress to find what helps you most.
Impact on Brain Activity
TMS can either increase or decrease activity, depending on the frequency used.
For depression, TMS delivers high-frequency pulses — typically 10–20 Hz — to underactive regions like the left prefrontal cortex.
This boosts activity in areas responsible for mood regulation, motivation, and decision-making, helping lift emotional numbness and improve energy over time.
For anxiety, PTSD, addiction, or OCD, TMS delivers low-frequency pulses — usually around 1 Hz (or 1 pulse per second) — to overactive areas like the right and medial prefrontal cortex and anterior cingulate cortex.
This gently reduces brain activity in those regions, helping reduce urges, racing thoughts, and emotional overwhelm. By tailoring the frequency and target area, TMS offers a personalized approach to balancing neural activity across different conditions.

Types of TMS Therapy
Each type of TMS therapy works a little differently — some go deeper into the brain, others act faster, and some target both sides of the brain at once. But, all types of TMS can be adjusted in intensity and frequency to either stimulate underactive areas or calm overactive ones, depending on your symptoms. Your care team will help match you with the right approach and fine-tune based on progress for lasting relief.
Repetitive TMS (rTMS)
rTMS is the most established form of TMS, using steady, repeated pulses to target specific brain areas. It’s especially effective for depression and offers a reliable, well-researched option for those who haven’t responded to medication.
Deep TMS (dTMS)
dTMS uses a specialized helmet-like coil to reach deeper and broader areas of the brain. This makes it ideal for more complex, co-occurring, or treatment-resistant cases.
Theta Burst Stimulation (TBS)
TBS is a newer form of TMS that delivers short bursts of magnetic pulses in patterns that mimic natural brain rhythms — achieving similar results to rTMS quicker (as little as 3 minutes).
Bilateral TMS
Bilateral TMS stimulates both sides of the brain, either one after the other or at the same time. It’s often used for conditions that affect mood and cognition on a broader scale, such as bipolar depression or severe, treatment-resistant depression. It may help when single-sided approaches fall short.
Is TMS Safe?
Yes, TMS is safe and one of the most well-tolerated treatment options available for serious mental health conditions. It’s FDA-approved, non-invasive, and doesn’t involve medication or sedation. TMS doesn’t hurt or give off radiation.
The most common side effect is mild scalp discomfort or lightheadedness during treatment, which usually fades quickly. There is no downtime needed after treatment.
If you’ve tried multiple medications without relief — or you’re tired of side effects — TMS offers a different approach with a strong safety record and promising results.
Who TMS is NOT For
TMS may not be right for people with metal implants in or near the head (excluding dental work), a history of seizures, or certain neurological conditions. Your care team will do a full screening to make sure it’s safe for you.
Indiana Center for Recovery offers more than just TMS. If it’s not the right fit, you’ll still have access to cutting-edge, evidence-based options like Spravato® Ketamine Therapy, Biofeedback, EMDR, and GeneSight® testing to take the guesswork out of mental health medication. We’ll help you find what works best for you!
Yes, Treatment Is Covered By Insurance
Treatment here is usually in-network, so any cost to you is as low as possible — sometimes even zero. No one will be notified if you reach out. And, there’s no commitment to get answers.
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