Key Benefits of NAD+ During Detox
Most patients report feeling clearer, calmer, and more physically stable — sometimes even after just one infusion. It’s not a miracle cure, but it makes a real difference during one of the most challenging parts of recovery.
- Reduces physical withdrawal symptoms
- Eases anxiety, cravings, and brain fog
- Restores mental clarity and mood
- Replenishes energy and improves sleep
- Supports brain function and cognitive repair
- Helps repair cellular damage caused by substance use
- All-natural and non-addictive
What to Expect During a NAD+ IV Session
The first days of detox are often the hardest. When your body is stressed and your brain chemistry is off. NAD+ IV Therapy helps bridge that gap — giving your system a head start while the rest of your treatment begins working.
An NAD+ IV doesn’t replace therapy, support, and other medications.
Your treatment plan during detox also includes comfort medications to ease symptoms — like ondansetron for nausea, hydroxyzine for anxiety, and buprenorphine for opioid withdrawal cravings.
Beyond medications, you receive chef-prepared meals and one-on-one support from masters-level therapists to help manage any cravings, stress, or emotional discomfort that comes up.
Is NAD+ IV Safe?
Yes. NAD+ is a substance your body already makes naturally. The IV just gives your system a boost when it’s at its most depleted.
Side effects are rare and usually mild (such as slight nausea or flushing during infusion). Our medical team ensures treatment is tailored and adjusted to your comfort.
The Research
The research on NAD+ IV therapy for detox has been growing in the last five years. In one early retrospective study, participants reported a nearly 70% reduction in cravings over a 10-day treatment period. The study also noted improvements in withdrawal symptoms like anxiety and depression, with no adverse events reported. ⓘ
Getting NAD+ IV Therapy
NAD+ IV Therapy is just one part of a safe, comfortable detox. Most detox centers do not offer any form of IV therapy. If you want to clear drugs or alcohol and retore brain function fast, give us a call. People travel in from across Indiana and surrounding states like Illinois for a science-based medical detox.
If you also want to tackle underlying issues, our inpatient or outpatient rehabs offer other advanced treatment options – including TMS therapy, Genesight, Spravato, EMDR and Biofeedback.
Deeply Experienced, Nationally-Recognized Detox Experts

Dr. Michael Kane MD
Chief Medical Director (Psychiatrist)
Double board-certified in Psychiatry and Family Medicine, Dr. Kane brings over a decade of experience treating complex mental health issues. Featured in Newsweek, PsychCentral, and MSN, he’s known for helping people feel seen, while delivering real results through medication and advanced therapies. Patients trust him to treat the whole person, not just the symptoms.

Jackie Daniels LCSW
Director of Clinical Development (Therapist)
Jackie is a licensed therapist, national speaker, and in long-term recovery herself. With 20+ years of clinical experience, she’s led major statewide efforts—like expanding Naloxone access and launching Indiana University’s first Collegiate Recovery Program. She’s known treatment models that is not only evidence-based but deeply rooted in lived experience.
Yes, Treatment Is Covered By Insurance
Treatment here is usually in-network, so any cost to you is as low as possible — sometimes even zero. No one will be notified if you reach out. And, there’s no commitment to get answers.
Verify Your Insurance